Experimental reconstruction of a neutral network for a protein-protein interaction
The structure of fitness landscapes — the mapping of DNA or protein sequences to organismic fitness (or a proxy) — is a central problem in evolutionary biology. Even in this … Continue reading
27/04/2015 · Leave a comment
On the coupled evolution of protein folding and binding
Michael Manhart and Alexandre V Morozov uploaded on bioRxiv their latest manuscript titled: Protein folding and binding can emerge as evolutionary spandrels through structural coupling http://dx.doi.org/10.1101/008250 where they show the … Continue reading
26/08/2014 · 4 Comments
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